This document explains the Cosmelan® depigmenting treatment performed at Leyla Skincare & Beauty, its potential effects, required aftercare, and your responsibilities as a client/patient. Please read it carefully.

Brief Explanation of the Treatment

Cosmelan® is the professional depigmenting method by mesoestetic designed to unify skin tone and reduce melanin-based pigmentary imperfections localized on the face. This method features an exclusive combination of highly effective active ingredients that provide a unique, dual-action mechanism: it visibly removes and attenuates dark spots while regulating pigment overproduction to control their reappearance.

The Cosmelan® method consists of two phases:

• In-clinic phase: A single in-office session where the aesthetic professional applies the intensive depigmenting mask. Afterward, the client returns home and leaves the mask on for the specific time indicated by the professional.

• At-home phase: Under the strict guidance and recommendations of the professional, the patient must follow a daily application routine for 6 months using the complementary cosmeceuticals of the method, which may vary depending on the phase and the treatment’s progress. The goal of this phase is to achieve continuous depigmenting action and long-term regulation of pigment overproduction.

Contraindications

• Pregnant or breastfeeding women.

• Hypersensitivity to any of the components of the various products included in the pack.

• Autoimmune diseases, decompensated chronic diseases, and/or active dermatological conditions in the treatment area.

• Individuals undergoing treatment with isotretinoin or other oral retinoids.

• History of skin hypopigmentation, including vitiligo.

• Active bacterial, viral, and/or fungal infections in the treatment area.

• Recent dermatological surgery in the treatment area.

• Open or semi-open wounds in the treatment area.

• Individuals with an unstable psychological profile.

I DECLARE that the following points have been explained to me:

1. The Cosmelan® method is indicated for superficial melanin-based hyperpigmentation, including melasma, post-inflammatory hyperpigmentation, lentigines, and ephelides (freckles). In my specific case, the professional has determined that this treatment is the most appropriate, although alternative options may exist for other scenarios, which I have had the opportunity to discuss with the professional. Considering the pros and cons of each, I have chosen the treatment described above.

2. The duration of the treatment and/or the amount of product communicated to me as necessary to achieve the desired effect is an estimate. It is impossible to know beforehand the exact amount of product or treatment period required due to the individual response of each patient.

3. The professional has explained to me that the regulation process requires time and effort. I am aware that to achieve optimal results, and to perfect and prolong the results obtained in the clinic, it is strictly necessary to follow the protocol for both the in-clinic and at-home treatments. Therefore, it is important that I attend all scheduled appointments at the center so they can monitor my progress throughout the treatment and adjust the homecare regimen as needed.

4. No other products should be used during the Cosmelan® method without the express recommendation of the professional to avoid adverse interactions. The treating professional will determine at all times the complementary products to be used, as well as the frequency of their application.

5. Throughout the duration of the treatment, direct and excessive exposure to natural or artificial light and heat sources must be avoided, as well as the use of saunas or swimming pools. Hair removal treatments or other procedures involving abrasive or irritating substances must also be avoided.

6. During the use of the Cosmelan® method, the daily application of a very high-level broad-spectrum sunscreen is mandatory. It is recommended to reapply it every 2-3 hours during daylight hours. This application routine should be maintained as a standard photoprotection practice even after the treatment concludes.

7. Despite the proper selection of the technique and its correct execution, RISKS AND COMPLICATIONS described by medical science as inherent to this treatment may occur. Among the primary risks explained to me are the following:

   • Risks and complications common to any aesthetic treatment, including but not limited to: allergic reactions to the substance used (usually mild, subsiding with proper treatment or even without treatment).

   • Specific risks and complications of this treatment that have been explained to me, and which I assume and accept: pain, burning, stinging, itching, peeling/flaking, scabbing, erythema (redness), edema (swelling), acneiform eruptions, dyschromia, and hyper- or hypopigmentation in the treated area.

8. Furthermore, I have been informed that it is crucial to disclose my personal history of medication allergies, current medications, pregnancy or breastfeeding status, history of facial herpes simplex, personal or family history of keloids, or any other relevant circumstance. Unforeseen risks or complications following the treatment may arise due to my personal circumstances, prior health condition, age, profession, etc.

I UNDERSTAND that the goal of the treatment is to improve my appearance, with the possibility that some imperfections may persist and that the outcome may not be exactly what I expected. In this regard, I am informed that the aesthetic result of the treatment depends on factors such as hormonal or vascular changes, genetic predisposition to hyperpigmentation, previously performed depigmenting treatments, sun exposure habits accumulated over the years, and even the presence of concomitant conditions (e.g., food intolerances). I am aware that no one can guarantee absolute perfection or safety regarding the results of aesthetic treatments. I understand that the result may not meet my expectations, and I acknowledge that no such guarantee has been made to me whatsoever.

I ACKNOWLEDGE that during the course of the treatment, unforeseen conditions may arise that necessitate a change from the original plan. In the event of complications during the treatment, I authorize the center to seek the necessary assistance of other specialists, according to their best professional judgment.

I COMMIT to faithfully following the professional’s instructions before, during, and after the aforementioned treatment, taking full responsibility for compliance with the post-treatment measures recommended by the reference center.

I ATTEST that I have not omitted or altered data when providing my medical and surgical history, especially regarding allergies and personal health risks or diseases.

I AUTHORIZE the taking of photographs of the treated area, which may be used for scientific, educational, or medical purposes, with the understanding that their use will not constitute any violation of my privacy or confidentiality rights.

I CONFIRM that I have understood the explanations provided to me in clear and simple language, and the professional attending me has allowed me to make all necessary observations and clarified all the doubts I raised. I have also been informed of, understood, and accepted the scope, risks, and contraindications described for the treatment. I also confirm that I have fully read and understood this CONSENT DOCUMENT, reaffirming each and every one of its points.

Furthermore, I have been informed of my right to refuse the treatment or revoke this consent.

Under these conditions, I CONSENT to the professional Leyla Guerrero (representative of leylaskinandbeauty.com) and her team performing the mesoestetic® Cosmelan® treatment on me.